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Where are keratinocytes located?

  1. Dermis

  2. Stratum corneum

  3. Subcutaneous layer

  4. Stratum basale

The correct answer is: Stratum corneum

Keratinocytes are cells located in the stratum corneum, the outermost layer of the epidermis. The dermis (option A) is the layer below the epidermis and does not contain keratinocytes. The subcutaneous layer (option C) is the deepest layer of the skin and does not contain keratinocytes either. The stratum basale (option D) is the deepest layer of the epidermis, but it contains cells called basal cells that eventually mature into keratinocytes and move up to the stratum corneum. Therefore, options A, C, and D are incorrect because they either do not contain keratinocytes or only contain precursor cells that eventually become keratinocytes.